Open Resection in Colorectal Cancer - Retrospective Study

Correspondence to: Daniela Radu:[email protected], M. Fernbach: [email protected], SUMMARY: Purpose: The present report was designed to evaluate how advanced colorectal neoplasm found at the moment of surgical treatment could represent a possible cause for high mortality rates. Main aim of this clinical study was to explore the current status of open surgery in the treatment of colorectal cancer. Major objectives followed in this review were: analyzation of the location and stage of colorectal tumours; frequency of colorectal neoplasm; identification of risk factors in relation to: age, grading, staging and comorbidity; evaluation of clinical and therapeutically characteristics in the cases studied. Methods: Retrospective study (2001-2008) of the surgical therapy results in colorectal carcinoma out of two surgical departments: Colo-Proctologic Centre of the Meschede City, Nordrhein-Westfalia County, Germany and First Surgical Department of the Timisoara County Hospital/Romania. This review is a non-randomized, retrospective, interventional and descriptive study who received surgery with curative or palliative intent. A total of 1084 patients with colon and rectum malignancy underwent treatment with current open devices and techniques. None of them became laparoscopic surgery. Results: Colon cancer including the rectosigmoid junction represented 73.24% of the cases, while those of the rectum generated 26.75% from the total number of studied cases. A high percentage of these tumours could be observed in males and females up entering the fifth decade of life. Median age of the patients at time that surgical therapy was performed was 68 years. Males had a higher risk for developing colorectal carcinomas. Half of the UICCstage I colon and rectum neoplasm had a G1-well differentiated grading. Recidive rates increased significantly with each successive grading class. Advanced tumours were indicators for a poor oncological prognosis. T3-tumours were the most frequent form of colorectal tumours found in all age groups (62.82%). Conclusions: The open resection in colorectal cancer is over the world performed by many surgeons. It still remains a safe and sure method for the treatment of bowel malignancy.